FCPS part one medicine june 2014 mcqs with answer

1. Esophageal stage of swallowing most effected by :

myasthenia

cerebral cortex stroke just above lateral gyrus

Scleroderma (correct answer)

2. cancer cells combatted by :

natural killers  (correct answer)

cd8 and t lymphos

cell mediated

3. TCA.... what is false:

A. sedation

B. alpha blocker

C. Sympthomimetic (correct answer)

D. beta agonist activity

4. DIC is stimulated by??

tissue thromboplastin (correct answer)

5. Thiazides causes..

Hypokalemia (correct answer)

Hyponatremia

Hypocalcemia

6. Hyperpolarization is caused by..

Na+ influx

K+ influx

Cl- influx (correct answer)

7. Pt of chronic renal failure going to dialysis..normocytic normochromic

anemia .. Drug given:

Erythropoietin (correct answer)

Folic acid

Vit b6

Vit b12

8. Tricuspid auscultation area?

A. 2nd right ic space

B. 2Nd left ic space

C. 3Rd left ic space

D. Mitral area

E. Lower half of left border of sternum (correct answer)

9. Parotid ducts opens into

Second upper molar teeth between cheeks and teeth (correct answer)

10. Histamine releasing opioid analgesic.

 Morphine (correct answer)

Tramol

butyrophenie

fentanyl

11. MRSA sensitive to:

aztreonam

co amoxiclav

clotrimoxazole (correct answer)

metronidazole

12. primary hepatocellular carcinoma :

aflatoxin b1

hep E

hep C (correct answer)

alpha 1 antitrypsin deficiency

13. Brodman area 3 1 2

1 recieves all somatic sensation (correct answer)

2 special sensory

3 granular cortex something

14. serology not helpful in

a) toxoplasmosis

b) ambisis

c) giardiasis (correct answer)

d) ameobic liver abscess

15. Virus causes cancer via

1 proto oncoogene

2 oncogene (correct answer)

3 nucleic acid

4 promotr gene

16. Byssinosis occurres in people working in

1)garment factory

2)lead factory

3)textile industry (correct answer)

4)cement factory

17. OPD , 2 year old boy comes with fever, bowel disturbance... mcv mch

mchc all raised ... detected by

serum vit b12 levels (correct answer)

intrinsic factor antibodies

18. 1st line phagocyte in blood

neutrophil (correct answer)

monocyte

macrophage

19. old aged Person living at 12000ft had a hx of of MI 6 year back...both

lower limbs swelling and bluish discoloration ...cause

A. cardio-pulmonary failure (correct answer)

B. venous thrombosis

C. CO Poisoning

20. a lady delivered 34 weeks baby who was at 30th percentile of weight

and height, cleft lip cleft palate, microcephaly , 6 fingers in both hands ...

axial something ... whats the diagnosis :

a: 45X

b: 46XXy

c: 74 XY+13 (correct answer)

d: 74 XY + 18

21. vitamin b12 def can be found out by urine test of

methylmalonic acid (correct answer)

pyruvic acid

22. a patient known case of lambago comes with sudden left side chest

pain.. Cardiac enzymes r normal.. No retrosternal pain also not radiated..

But tenderness at 5,6 intercostal spaces at posterior side..

MI

Costochondritis (correct answer)

Aortic aneurysm

Pleuritis

23. There is lesion of upper trunk.. All will occur except adduction of arm

medial rotation of arm

Sensory loss over forearm

Elbow extension

Supination (correct answer)

24. Typhoid diagnose in 2nd week best by :

widal

blood cs

blood cs plus widal (correct answer)

only widal

stool cs

25. Pt with nose lesion , granuloma, proteinuria

leprosy

wegner's (correct answer)

26. Which hormone not required for growth of sperm:

GH (correct answer)

bHCG

Prolactin

FSH

27. Steatorrhea due 2 chronic pancreatitis occur due to deficient:

amylase

lipase (correct answer)

28. Female with lush push bodyline , well develped brest ,, complained

amenorrhoea since puberty , short vagina , uterus not palpable, testes in

inguinal region.

male psuedohermaphrodite

female pseudoherma

testicular feminization (correct answer)

29. Dissection of aorta:

medial necrosis  (correct answer)

30. Subclavian artery arches over

clavicle

1st rib (correct answer)

2nd rib

31. What’s the hallmark of aids:

progressive immune-depression (correct answer)

opportunistic infections

32. in tractus solitarius

A. 1st order neuron of taste (ant 2/3 tongue)

B. 2nd order neuron of taste (ant 2/3 tongue) (correct answer)

33. wound healing

ascorbic acid (correct answer)

34. Autosomal dominant. whats wrong:

50% offspring effected

complete penetrance

50% females effected

Variable expression (correct answer)

35. radiation causes cancer usually in :

5-10 yr (correct answer)

more than 10 yrs

36. what white blood cells are raised in acute viral infection

A. Neutrophils

B. Lymphocytes (correct answer)

37. protein fat carbohydrates deposition by

A. GH

B. glucagon

C. insulin (correct answer)

38. Appendix ..pain in flexion & Medial Rotation of hip.

 Pelvic (correct answer)

Retrocecal

Preileal

Post ileal

39. body utilizes nutrients in what order:

CHO, fats , protein (correct answer)

fat, prot CHO

cho Prot fat

40. myasthenia gravis Pt, Dr gv some medication due to which Pt conditions

improved. What’s mode of action of medication:

anticholinesterase (correct answer)

chlonergic

anticholinergic

41. Skeletal muscles

A. are innervated by somatic nervous system (correct answer)

B. are non straited

C. intercalated disc

42. Shock characteristic:

tissue hypoxia (correct answer)

low BP

tachycardia

43. Scenario about nerve supply to tip of the nose

Opthalmic division of trigeminal nerve (correct answer)

44. Neurogenic shock mediated by:

loss of vasomotor tone (correct answer)

heart pumping decrease

45. Scenario on lacrimation while eating like that

Facial nerve (correct answer)

46. Question about

 secondary active transport

Amino Acid absorption in PCT  (correct answer)

47. what sound comes on rapid filling of lft ventricle

S3(correct answer)

S2

48. 70 yeard old lady...vision not clear

A. Cataract(correct answer)

B. Stabismus

C. Astigmatism

49. If Ejection fraction increase

EDV decrease

ESV decrease(correct answer)

50. Woman with borderline lab values of MCV, MHCH etc:

microcytic normo

macrocytic macro

microcytic hypochromic

51. Lumber puncture ...predominates lymphocytes, HIGH Protein & NormalGlucose

A. TBM(correct answer)

B. Bacterial meningitis

52. Nutrient artery supplies:

A. epiphyseal plate

D. flat plate

C. epiphysis

D. Diaphysis (correct answer)

E. metaphysic

53. Vitamin K deficiency, defective clot formation

A. fibrogen

B. fibrin

3. thrombin

4. thromboplastin

5. Prothrombin(correct answer)

54. Osteogenic imperfecta

Defect in synthesis of collagen

55. liver in its place coz of

attachment with IVC ligaments(correct answer)

56. Jugulodiagastric lymph node drains into

Palatine tonsils and tongue(correct answer)

57. Right adrenal gland

Pyrimidal in shape(correct answer)

58. oblique fissure in lung extends from :

t3 - t6

t2 t6

t4 t6

59. inappropriate about adrenal gland

neonate adrenal is same the size of adult adrenal gland

60. factor 9 def, aptt high PT low

Christmas disease

factor 8 def

61. sixty year old lady having unilateral severe head ache...temporal atery

biopsy

A. Giant cell artiritis (correct answer)

B. Takayasu

62. bile acids

absorbed in ileum(correct answer)

63. bile acids helps fat digestion by:

Facilitate absorption of Lipid(correct answer)

Hydrolysis of LIPID

64. stone in the parotid duct

Apoptosis(correct answer)

necrosis

degeration

65. Artificial respiration is not necessary if lesion occur at..

 A.c2

B.c3

C.abovec5

D.below c5(correct answer)

66. epithelium changes in endocervix

Metaplasia(correct answer)

dysplasia

67. Squamous cell Carcinoma

marjolin ulcer

bowen's disease(correct answer)

68. Peroxisomes

Long chain fatty acid(correct answer)

69. Pt for renal transplant , what investigation is not necessary in the donor:

Serum Renin(correct answer)

UCE

HLA

CBC

70. Hormone involved in gluconeogenisis

Glucagon(correct answer)

71. Inhibit gastric acid secretions

Secretin(correct answer)

72. Naked Person with 80% humidity in air & 21 degree temp:

heat loss by

A. conduction and radiation(correct answer)

B. By vaporization of sweat

C. Elevated metabolism

D. Respiration

E. Urination

73. Derived from neural crest

autonomic ganglia(correct answer)

74. Rapidly adopting fibers... A. baroreceptors,

B. pacinian corpuscles, (correct answer)

C.meissner

75. Nutritional deficiency..scaly dermatitis,alopecia

Zinc(correct answer)

76. Not supplied by vagus nerve (Asim’s MCQ)

A. stomach

B. ascending colon(correct answer)

C. Jejunum

77. Which will shift the O2.HB curve to the extreme left...

A. CO poisoning(correct answer)

B. fetal Hb ,

C. acidosis,

D. inc 2,3 bis

78. Secretary vesicles found in organelle

A. Golgi apparatus (correct answer)

B. ER

79. Cristanee concavity toward nucleus

Golgi apparatus(correct answer)

80. Inappropriate about atropine..

A. Increase CUTANEOUS BLOOD FLOW(correct answer)

B contraindicated in inc intra-ocular pressure

81. Widest part of epidural space

A. L2(correct answer)

B. C7

82. About collagen.... most abundant protein in the body(correct answer)

83. High pressure oxygen for 24 hrs (Scenario of Some Smoker).

Spontaneous Pneumothorax(correct answer)

84. Warfarin given for DVT, what is Appropriate?

Not given in pregnancy(correct answer)

Rapidly antagonized by FFP

85. 5th week what happens?

A. Heart has definite form

B. Limb buds appear

86. Neural tube is formed in which week

A. 3rd

B. 4th(correct answer)

C. 5th

87. 2*2 TABLE

Chi-square testing(correct answer)

88. Sample which is age based grouped then random people taken from

each group, IT IS?

A. stratified sampling(correct answer)

B. simple sampling

89. Meningitis after pyogenic lung abcess organism?

A. Staph(correct answer)

B. Pneumococci

90. Endometrial hyperplasia

A. inc estrogen(correct answer)

B. dec estrogen

C. inc progesterone

91. PYOGENIC PEROTINITIS

A. Bacteroids(correct answer)

B. E.Coli

92. Organ with high atriovenous (AV) 02 difference at rest?

A. Heart(correct answer)

B. Kidney

C. Brain

D. Skeletal muscle

93. Hormone that stores carbohydrates, lipids and proteins in cells is also

called hormones of abundance

A. GH

B. Cortisol

C. Thyroid hormone

D. Estrogen

E. Insulin(correct answer)

94. Starling law of heart

A. Explain the increase in cardiac output that occur when venous return is

increased(correct answer)

B. explain the inc in heart rate by exercise.

C. does not operate during exercise.

D. explains the increase in cardiac output when the sympathetic nerves supplying

the heart are stimulated.

E. does not operate in the failing heart.

95. Trigeminal ganglia

A. Completely covered by dura

B. Freely bathed in csf

C. Lies in MCF on the side of cavernous sinus(correct answer)

96. Short limb..short height...intelligence normal (case of achondroplasia)

A. Autosomal dominant(correct answer)

B. Autosomal recessive

97. Drug which enhances the hypoglycemic effect of sulphonylurea?

A. Phenylbutazone, (correct answer)

B. thiazide.

C. OCP

98. Tx of hypercalcemia

A. Calcinomimetic

B. Bisphosph

C. Furesimide(correct answer)

99. 45x0/46xy....A short stature n prominent crease line...

A. BRACHECEPHALY AND MENTAL RETARDATION

B. GONADAL DYSGENESIS WITH FOLLICULAR APLASIA(correct answer)

100. Neostigmine action: inhibit Ach esterase(correct answer)

101. Venous return increased by

A. intrathorcic pressure

B. Valve in veins

C. Muscle contraction of leg(correct answer)

102. A LADY HAD AN ROAD ACCIDENT AND GOT HEAD INJURY.SHE LATER

DEVELOPED complaint of polydypsia and polyuria..lab findings were

given in which urine osmolarity is low and plasma osmolarity high. After

giving vasopressin urine osmolarity increased and plasma osomalilty

decreased…what is diagnosis???

A. Central Diabetes Insipidus(correct answer)

B. SIADH

C. Nephrogenic Diabetes Insipidus

103. Chrons disease diff from Ulcerative colitis

Perianal lesions(correct answer)

104. An immunocompromize pt developed s/s of pneumonia BAL fluid

revealed boat shaped cyst organism (Nov 2013 Medicine paper MCQ = repeated)

A) Toxoplasma gondii

B) H. influenza

C) Pneumocystis carinii(correct answer)

105. Hormone inhibited by feedback from hypothalamus? Prolactin(correct answer)

106. Pneumothorax

Ipsilatrral lung collapse and chest wall spring out(correct answer)

107. A patient burning and recovered completely what factor determines that

complete recovery will occur?

A. underlying Granulation tissue(correct answer)

, B. local edema

C. Blood supply

108. Typhoid test

A. 1:160 O antigen

B. 1:160 H ag

C. 1:80 O ag

D. 1:160 O and H antigen(correct answer)

109. Pt unable to invert his foot while the lateral rotation is intact structure

involved

A. tibialis ant & tibialis post(correct answer)

B. tibials ant & fallicus H longus

110. What happen in lower motor neuron lesion..??

A.muscle wasting.. (correct answer)

 B.hypertonia..

111. Vomiting center situated

Medulla oblongata(correct answer)

112. Lower motor neuron lesion

A. Decrease motor tone(correct answer)

B. spastic

113. Chorea, athetosis region involved

Basal ganglia(correct answer)

114. a lady have difficult in going down stairs examination shows head tilted

to left and rite eye was upward ocular musle involved?

A.right sup oblique.. (correct answer)

B.inf rectus..

C. sup rectus

115. Area of the brain most activated before performing skilled motor activity

A) Precentral gyrus

B)spinal motor neuron

C) cerebellum.

D) Cortical association areas (correct answer)

116. pupillary light reflex carried by..

A. 2nd & 3rd Cranial Nerves(correct answer)

B. 3rd and 4th CN

117. Some Scenario of unilateral muscle atrophy with no sensory loss..lesion is:

A. upper motor neuron

B. Lower motor neuton

C. Lower motor neuron with ant horn of spinal cord(correct answer)

118. Asthma .. Dec FEV 1/FVC 75(correct answer)

119. Pt with chemotherapy induced vomiting drug to b given

1)metoclopramide

2)domeperidon

3) OndaNsetron(correct answer)

120. Artery in TRUE PELVIS

Middle rectal artery(correct answer)

121. Estrogen is released by?

A. ovary(correct answer)

B. uterus

122. Which is malignant?

A. Glioma(correct answer)

B. Meningioma

C. H. mole

123. Clostridium perfingens exotoxin action by..

A. coagulase .

B. phopholipase(correct answer)

124. Pt with bronchial ca present with hemoptysis due to??

A) Erosion of bronchial vessel(correct answer)

B) pulm vein

C) pulm artery.

125. Cavernous sinus thrombosis

A. superior opthalmic vein(correct answer)

B. inferior opthalmic vein

126. Inappropriate about hcg..

A. It causes ovulation..

B. Little similar as thyroid,

C. it causes LEUITINIZATION OF FOLLICLES(correct answer)

127. major part of energy utilized during breathing is to overcome

A. Elastic recoil of lungs(correct answer)

B. Resistance of chest wall

C. Large airway resistance

128. Side effect of chlorpromazine..

A. dystonia(correct answer)

129. Immunological function is significantly reduced in

A. dec basophils

B. ACTH(correct answer)

C. dec neutrophis

D. liver failure

130. Patient came with complaint of hirsutism .muscle wasting .skin

pigmentation and truncal obesity, hyprtension hyprglycemia...

A.Cushing disease

B. Primary inc in ACTH(correct answer)

131. Decrease in PR interval

A. 1st degree Heart Block

B. 2nd degree Heart Block

C. WPW syndrome(correct answer)

132. Slow Pain transmitted by unmyelinated c fibers..

A. substance p(correct answer)

B. serotonin

C. Ach

133. Which hormone decrease gastric motility..???

A. CCK .. (correct answer)

B secretin..

C. gastrin

134. Minimal change nephrotic syndrome...microscopic finding

A. mesengial deposition

B. sub epithelial deposition

C. sub endothelial deposition

D. Linear IgG deposition on IMMUNOFLORESCENCE (correct answer)

135. Fracture behind humeral medial epicondile loss of sensation in

A) medial/3palmer aspects

B) Medial 1/3 palmer & dorsal aspect(correct answer)

C) Lateral 1/3

136. A sluggish pendular knee jerk due to..?

A. Anterior horn neurons damage(correct answer)

B. upper motor neuron lesion

137. aortic opening aneurysm structures compressd...

azygous vein and thoracic

duct(correct answer)

138. Microaneurysm feature of AIDs don’t include..

A. hard exudates(correct answer)

B. Vasculitis

139. Thymus

rich in lymphocytes(correct answer)

140. Aids not associated with..

A squamous cell carcinoma..

B lymphoid series of bone marrow (correct answer)

141. Lymph nodes not present in?

A. Spleen

B. Thymus(correct answer)

142. Basic drugs bind to..??

A. alpha 1 glycoprotein..

B. albumin

143. Thrombocytopenia APPROPRIATE

A. inc clotting time causing dec platelet count

B. thrombocytonpenia impairs APTT pathway

C. DIC occurs due to Dec in platelet count/ DIC causes decrease in platelet

count(correct answer)

144. A child with thrombocytopenia after acute viral infection due to....

A. Anti-platelet antibody (correct answer)

B. immune complex formation.

C. consumptional coagulopathy

145. Minimal change in blood flow to an organ during exercise

A) Heart

B) Brain

C) Skeletal muscles

D) Kidneys.

E) Lung.

146. Congenital anomaly associated with urothelial CA is

A. bladder extrophy (correct answer)

B. unilateral agenesis of kidney

C. double ureter

D. Horse shoe kidney

147. Lipoprotein with highest cholesterol content

A) HDL

B) LDL(correct answer)

C) IDL

D) VLDL

E) Chylomicrons

148. about leprosy drugs which of the following is Inappropriate

CLOFAZIMINE IS NOT GIVEN IN PT RESISTENT TO DAPSONE (correct answer)

149. Galactorrhea (Asim’s MCQ with little modification of question stem)

A. Chromophoes are smallest(correct answer)

B. chromophils are 50% of total

150. Scenario of turner syndrome.

A. bracheceephale with mental retardation

short stature with prominent simian crease

B. gonadal dysgenesis with follicular aplasia(correct answer)

151. Inappropriate about dopamine.

A: contraindicated in septic shock... (correct answer)

B. causes increase myocardial infarct area..

C. 10 microgram per kg dose of dopamine causes vasoconstriction

152. A vertical lesion in optic chiasma causes..

A bitemporal hemiaopia.. (correct answer)

B. right sided homonomous hemianopia

153. Warfarin causes decrease in..

A. Fibrinogen

B. Factor 13

C. Prothrombin(correct answer)

154. Essential amino acid is..

Phenylalanine(correct answer)

155. Atomic bomb,... release of Stroncium-90 which affect milk products..so it

causes

A.osteosarcoma(correct answer)

B.nasopharyngeak CA

3.leukemia

156. Vertical artery along face, deep to submandibular gland is..??

A. Facial

B. Maxillary

C. Lingual(correct answer)

157. Tumor which also invade neural tissue

A.adenoCA

B.hemangiopericytoma(correct answer)

158. which one is NOT autosomal recessive

A. ataxia talengiectasia

B. carcinoma ovary(correct answer)

159. good patient and doc relationship...

active listening(correct answer)

160. One glucose give ATP..

A. 38 (correct answer)

161. Digoxin don't cause

A. inc intracellular Ca

B. inc intracellular Na

C. inc intracellular K(correct answer)

162. inferior thyroid artery is

branch of thyrocervical trunk(correct answer)

163. Pt with gum bleed in petechia advised bone marrow likely DX

A) Lymphoma

B) Leucopenia

C) Leukemia(correct answer)

164. fluid having specific gravity of 1.006 cause is

A. CCF (correct answer)

B. Ca lung

C. pneumonia

D. TB

165. a patient came in semi comatose state,,shifting dullness was

positive..liver biopsy taken and there were mallory bodies n fibrosis of

liver :

Alcoholic Hepatitis(correct answer)

166. A lady after abdominal surgery presented with dyspnea susp DVT cause

(Asim’s MCQs)

A) Endothelial injury

B) Endothelial injury & stasis

C) Stasis & hypercoagulablity. (correct answer)

167. Broadman’s Area 3 2 1,,,

A. agranular cortex..

B. Primary Somatosensory Cortex(correct answer)

168. secondary center of ossification (Asim’s MCQ)

EPIPHYSIS(correct answer)

169. acclimatized...rapid ascent

a) 2 3 DPG(correct answer)

b) PO2 is normal

c) PO2 is lower than normal

d) Pulmonary edema

170. Pregnant lady with normocytic normochromic Anemia. Cause?

plasma volume expansion(correct answer)

171. Adrenal insensitivity syndrome which is inappropriate test

A. Serum LH FSH

B. Serum progesterone(correct answer)

C. US abd

172. Endocervical epithelium of lady reveals sq epi cause?

A) Dysplasia

B) Anaplasia

C) metaplasia(correct answer)

173. Water Intoxication causes???

A) Slow pulse(correct answer)

B) Thirst

C) Altered behavior.

174. In complete heart block

A. Atrial rate is lower than ventricular rate

B. Ventricular fibrillation is common

C. Fainting occur cuz atrial unable to pump blood into ventricles

D. Fainting occur because of prolong periods during which ventricles fail to

Contract (correct answer)

175. Burning hot sensation occurs when temp of the surrounding is

A.28

B.32

C.42

D. Above 45 (correct answer)

176. Slow growing Tumor/Carcinoma of Thyroid?

A. Follicular

B. Papillary(correct answer)

177. Low molecular weight heparin

A) can cause thrombocytopenia

B) produced by fragmentation n degradation of heparin(correct answer)

178. Clostridium tetani main site of action is?

A.cerebral cortex

B.Exotoxin produces lethal effects(correct answer)

179. Pt having Hypertension 210/120 and Creatinine 7, defect is in?

A. JG apparatus (correct answer)

 B. Mecula Densa

180. Gastrectomy after 3 months anemia

A. microcytic hypochromic

B. megaloblastic(correct answer)

181. Drug contraindicated in impaired renal failure:

` Gentamicin(correct answer)

182. Solubility of drug is increased by which factor

A. increase lipid solubility(correct answer)

183. Gastric secretions are inhibited by what.

A. secretin(correct answer)

B. Ach

184. In slow wave sleep what is unlikely.

A. Inc muscle tone(correct answer)

B. Dreams unable to recall

C. Delta waves

185. Bradykinin ...

A. kallikren(correct answer)

186. Alpha adrenergic stimulation causes

A.. Vasodilation

B. Lipolysis

C. Pupillary dilation(correct answer)

187. GFR Clinically Measure by:

A. Creatinine(correct answer)

B. Inulin

C. PAH

188. Inappropriate regarding Azygous Vein

Pass through Esophageal Opening(correct answer)

189. Rh Agglutinins

A. present of RBC surface(correct answer)

B. present in month of Rh -ve mother when give birth to rh +ve fetus

190. Artery involved Anterior wall MI

LAD artery(correct answer)

191. Taste fibers through.

tractus solitarius(correct answer)

192. After giving Glucocorticoids, there will be?

Decrease Lymphocytes(correct answer)

Decrease Neutrophil

193. Multiple long bone fracture...B.P 90/, Pulse 115. Initial management?

A. Fracture stabilization

B. Volume replacement(correct answer)

C. Tracheostomy

194. Atrial fibrillation

A. Pulses deficit(correct answer)

195. The process by which DNA is transferred from one bacterium to another

by a virus is known as

A. TRANSDUCTION(correct answer)